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Chemoselective Acylation and Benzoylation of Alcohols, Phenols and Amines using Copper Oxide under Solvent Free Condition

G. A. Meshram and V. D. Patil

Copper (II) oxide efficiently catalyzes chemoselective acylation and benzoylation of alcohols, phenols and amines with stoichiometric amount of acetyl chloride and benzoyl chloride under solvent free conditions and at room temperature. The remarkable selectivity under mild and neutral conditions, short reaction time, reusable, commercially available and inexpensive catalyst, are advantages