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COMPARISON OF ANTI-OXIDANT ACTIVITY OF ANDROGRAPHIS PANICULATA AND TINOSPORA CORDIFOLIA LEAVES

MEENU SHARMA and SUMAN JOSHI

This work mainly focus on the anti-oxidant potency of aqueous, methanolic and ethanolic extracts of two Indian medicinal plants (Andrographis paniculata and Tinospora cordifolia). The methanolic extracts of leaves of Andrographis paniculata showed promising anti-oxidant activity followed by ethanolic extracts of leaves of Tinospora cordifolia. Results suggest that the active anti-oxidant compounds are better extracted in methanol for Andrographis paniculata and in ethanol for Tinospora cordifolia. Results also suggest that there is a direct co-relation between the total polyphenols extracted and anti-oxidant activity. Free radical scavenging potential of various extracts (methanol, ethanol and aqueous) of A.paniculata and T. cordifolia were evaluated by using reducing power. In this method, ascorbic acid was used as a standard of determining reducing power. The methanol extract of the leaves of A. paniculata exhibited appreciable activity as compared to the aqueous and ethanol extracts, indicating that A. paniculata has promising free radical scavenging activity.