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DeterminationOf LomefloxacinBy Flow Injection Chemiluminescence

QU Ling-boa, Zhou Jie, LI Jian-jun


A rapid and sensitive flow injection chemiluminescence (CL) method is described for the determination of lomefloxacin hydrochloride based on the CL generated during its reaction with either cerium(IV) and sodium sulphite in acid medium (system1) or Ce(IV) in acid condition sensitized by rhodamine 6G (system2) or luminol-KIO4-calcein in alkali medium (system3).The effect of analytical and flow injection variabled on these CL systems and determination of lomefloxacin hydrochloride are discussed. The proposed procedures allow the determination of lomefloxacin hydrochloride over the following concentration range 0.01- 15.0 mg L-1 with a detection limit of 0.005 mg L-1, 0.10-15.0 mg L-1 with a detection limit of 0.06 mg L-1, 1.0-20.0 mg L-1 with a detection limit of 0.50 mg L-1 respectively. The method is successfully applied to the determination of lomefloxacin hydrochloride in pharmaceutical preparations.


索引于

  • 中国社会科学院
  • 谷歌学术
  • 打开 J 门
  • 中国知网(CNKI)
  • 引用因子
  • 宇宙IF
  • 电子期刊图书馆
  • 研究期刊索引目录 (DRJI)
  • 秘密搜索引擎实验室
  • ICMJE

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