抽象的

Metal complexes of salisylaldoxime: Preparation characterisation and biological activity

Sachin R.Joshi, S.P.Pachling, Seema I.Habib

Eight neutral complexes of Cu(II), Ni(II), Co(II) and Zn(II) have been prepared with a newheterocyclic Schiff base (PL) derived fromsalisyladldehyde and hydroxyl amine hydrochloride. The analytical data shows that the metal to ligand ratio is 1:2:1 formetal complex with oxime as a primary ligand and 1:2:2 for mixed heterocyclic ligand. The structural features have been determined fromIR, UV-Vis, 1H-NMR, and ESR spectral data.All the complexes exhibit octahedral geometry around the centralmetal ion. The molar conductance values of metal complexes suggest their non electrolytic nature. The free Schiff bases and their complexes have been tested for their antibacterial and antifungal activities against several human pathogenic bacteria and fungi, the obtained result showed enhancement in activity on coordination of metals with ligands.