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N-bromosuccinimide (NBS) catalyzed, microwave-assisted rapid synthesis of 1-amidoalkyl-2-naphthols under solvent-free conditions

Hassan Ghasemnejad-Bosra


An efficient and direct procedure has been developed for the preparation of 1-amidoalkyl-2-naphthols by a one-pot condensation of aryl aldehydes, naphtalen-2-ol and acetamide, in the presence ofN-bromosuccinimide (NBS) as a catalyst. The reactions were carried out under thermal condition and microwave irradiation in high yields. The present methodology offers several advantages such as excellent yields, simple procedure and eco-friendly reaction condition.


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  • 中国社会科学院
  • 谷歌学术
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  • 中国知网(CNKI)
  • 引用因子
  • 宇宙IF
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  • ICMJE

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