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New Biologically Active Transition Metal Complexes Of 2-Mercapto-4,6-Diamino-5-Hydroxypyrimidine

Sahar I.Mostafa, Nick Hadjiliadis


The reaction of 2-mercapto-4,6-diamino-5-hydroxypyrimidine(HMDAHP) with Fe(III), Ni(II), Ag(I),[RuII(PPh3)3Cl2] and[AgI(phen)(H2O)(NO3)] is described. IR, 1H NMR and mass spectra, conductivity, magnetic and thermal measurements of the complexes reported and their structures discussed. In all complexes, HMDAHP behaves as a bidentate forming four-membered cyclic nitrogen-sulfur chelate without any participation of the pendant amino or hydroxy groups in complexation. The biological activity of Ag(I) complexes against bacteria(S.aureus and P.aeruginosa) and fungi(A.niger and C. albicans) was also discussed.


索引于

  • 中国社会科学院
  • 谷歌学术
  • 打开 J 门
  • 中国知网(CNKI)
  • 引用因子
  • 宇宙IF
  • 电子期刊图书馆
  • 研究期刊索引目录 (DRJI)
  • 秘密搜索引擎实验室
  • ICMJE

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