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One Pot Synthesis of Antimicrobial Active New 2-Benzimidazolesulfonamide Derivatives from 2-Mercaptobenzimidazole

P. B. Gorepatil, Y. D. Mane, V. S. Suryawanshi, V. S. Shinde and V. S. Ingle

The H2O2 –PCl5 reagent system has been found to be an efficient reactive reagent for the one pot conversion of 2- mercaptobenzimidazole to 2-benzimidazolesulfonyl chloride with high purity. 2-Benzimidazolesulfonyl chloride on reaction with aromatic amines in the same pot results in the formation of corresponding new2-benzimidazolesulfonamides derivatives in excellent yields and in short reaction time