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Optimization of high hydrostatic pressure extract 1-deoxynojirimycin from mulberry leaves with response surface methodology

Zhang Pei-Qi, Zhang Li-Hua, Zong Wei


In order to optimum ultra high pressure extraction (UHPE) parameter of 1- deoxynojirimycin (DNJ) from mulberry leaves. On the basis of single-factor test, response surface methodology was used to optimum extraction parameter. The mathematical regression model is established about the dependent variable (extraction yield of DNJ) and independent variables (alcohol concentration, extraction time and extraction pressure) through Box-Benhnken center composite design and response surface methodology. The results indicated that the optimal extraction conditions were alcohol concentration of 73%, extraction time of 3min, extraction pressure of 400 MPa. Under these conditions, the maximum yield of DNJ was 0.0931%. ItÂ’s proved that UHPE was a suitable method for extraction of DNJ as its higher extraction yield and shorter time.


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  • 中国社会科学院
  • 谷歌学术
  • 打开 J 门
  • 中国知网(CNKI)
  • 引用因子
  • 宇宙IF
  • 研究期刊索引目录 (DRJI)
  • 秘密搜索引擎实验室
  • 欧洲酒吧
  • ICMJE

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