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Role of Molecular Redundancy in Modeling of Clostridium Histolyticum Collagenase Inhibitory Activity of Sulfonyl-1-Amine Hydroxamates

Shweta (Thakur) Rathore, M. L. Gangwal and Dinesh Paliwal


The present research paper deals with the role of molecular redundancy in modeling of CLOHI collagenase inhibitors. The regression analysis has shown that out of the pool of topological indices used, the MRI is the best one for protease inhibitor properties and this has been discussed on the basis of various statistical parameters.


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