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Silicon tetrachloride-induced green and efficientMCRprotocol for the synthesis of 1,8-dioxo-decahydroacridines and their transformation to novel functionalized pyrido-tetrazolo[1,5-a]azepine derivatives

Hanan A.Soliman, Tarek A.Salama


Green and efficient MCR protocol for the synthesis of 1,8-dioxodecahydroacridine derivatives was achieved through a one-pot, threecomponent condensation of dimedone, aryl amines and aryl aldehydes utilizing tetrachlorosilane (TCS) as catalyst under solvent-free conditions. Reaction of the titled compoundswith TCS-NaN3 to give novel functionalized pyrido[3,2-c]tetrazolo[1,5-a]azepine derivatives is also described.


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  • 中国社会科学院
  • 谷歌学术
  • 打开 J 门
  • 中国知网(CNKI)
  • 引用因子
  • 宇宙IF
  • 米亚尔
  • 秘密搜索引擎实验室
  • 欧洲酒吧
  • 巴塞罗那大学
  • ICMJE

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