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Study Of Factors Effects On Static Headspace Gas Chromatography

Yan Zheng, Xiao Jinjin, Cui Jianbo

Depending on the determination of ethanol and benzene in water, we studied the theory of static headspace gas chromatography, and discussed the effect of vapor-liquid phase ratio, distribution constant, equilibrium temperature, equilibrium time and inorganic salts on headspace concentration. The results showed that the effect of these factors on headspace concentration varied significantly in various volatile residual solvents in pharmaceuticals.