抽象的

Substituted quinolinones. 21. EfficientN-alkylation of 4-chloro-6-methylquinolin-2(1H)-one under phase transfer catalysis conditions

Alkylation reaction, Halo-methylene compounds, Quinolin-2(1H)-one, Tetrabutylammonium bromide, Phase transfer catalysis.

Selective and efficientN-alkylation reaction of 4-chloro-6-methylquinolin- 2(1H)-one with certain active halo-methylene compounds have been carried out using phase transfer catalysis (PTC) technique. Tetrabutylammonium bromide (TBAB), PTC catalyst, and potassium carbonate, base catalyst, were utilized to prepare eleven new1-alkyl-4-chloro-6-methylquinolin-2(1H)- ones. Structure of new compounds was established on lights of their analytical and spectral data.