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Synthesis, Characterization and Antibacterial Studies on Some Organometallic Complexes of Ruthenium (II) Ligated with 4-Amino-5-mercapto-3-substituted-1,2,4-triazole

R. N. Pandey and Nisha Kumari

Organometallic complexes of ruthenium (II) with the composition [RuCl(CO)(E φ 3 ) 2 L] and [Ru(E φ 3 ) 2 L 2 ] (E = P/As; LH = Phenyl/benzyl derivative s of 4-amino-5-mercapto-3-substituted-1,2,4- triazole) have been isolated using some precursor co mplexes. The structure of new chelates are deduced by elemental analysis, molar conductance, magnetic moment, IR, UV-vis and 1 H NMR spectral studies. IR spectral studies provides strong evidence in support of the deprotonated ligands with metal ion in a bidentate fashion through both N,S atoms of the thioam ide group in octahedral st ructure. The antibacterial studies of the ligands and their metal chelates have been screened for the selected bacteria, E. coli , B. subtilus and S. aureus . Studies suggest that the metal chelates are more active than ligands but lesser than standard drug streptomycin.