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Synthesis, Characterization and Biological Aspects of O-and N-Donor Schiff Base Ligands and their Co (II) & Zn (II) Complexes

Rajiv Kumar Singh and H. B. Singh

New cobalt (II) and zinc (II) complexes of O-and N-donor Schiff bases derived from furfuraldehyde and 2-aminopyridine (SB1) or hydrazine hydrate (SB2) have been synthesized. The ligands and their metal complexes have been characterized on the basis of elemental analysis, molecular weight determinations, molar conductance measurements, IR, 1H NMR and UV-vis. spectral studies. The purity of the compounds was confirmed by TLC. The Schiff base ligands act as non-functional bidentate and tetradentate donors and coordinate through furfural oxygen and azomethine nitrogen. These have also been screened for their in vitro antibacterial and antifungal activities against bacterial species like escherichia coli and Staphylococcus aureus as well as fungal species like Candida albicans and Asper niger by using disc diffusion method wherefrom the complexes have been found biologically more potential than the respective ligands.