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Synthesis of 3-Halo Flvones from 2-Hydroxy-3-5-Disubstituted Acetophenone

R. E. Bhadange, S. V. Kolhe and R. P. Ganorkar


Substituted acetophenone was reacted with substituted benzoic acid in pyridine medium as base in presence of phosphoryl chloride for five hours and the thick mass was decomposed by 1 : 1 HCl to get substituted benzoyloxy substituted acetophenone. This product was further subjected to BVT reaction to get substituted dibenzoyl methane. Substituted dibenzoyl methane is treated with iodine monochlorides in DMF medium gives 3-halo flavones.


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  • 中国社会科学院
  • 谷歌学术
  • 打开 J 门
  • 中国知网(CNKI)
  • 引用因子
  • 宇宙IF
  • 米亚尔
  • 秘密搜索引擎实验室
  • 欧洲酒吧
  • 巴塞罗那大学
  • ICMJE

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