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Synthesis of some Heterocyclic Compounds Derived from Chalcones

Mohamed J. Elarfi and Hussniyia A. Al-Difar

Chalcone derivatives were synthesized by reaction of some benzaldehyde derivatives with acetophenone, then the products obtained were allowed to react with urea, thiourea and hydroxylamine, to give the heterocyclic derivatives of oxazine, thiazine and isoxazole, respectively. The final products have been characterized by elemental analysis, IR and proton NMR spectra. These compounds were also screened for their antibacterial activities.